PTK6 (N-term) Peptide
产品名称： PTK6 (N-term) Peptide
英文名称： PTK6 (N-term) Peptide
产品编号： P2759
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTK6.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PTK6.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells.
Derry JJ, Prins GS, Ray V, Tyner AL.Oncogene. 2003 Jul 3;22(27):4212-20.
- 2.
- Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.
Coyle JH, Guzik BW, Bor YC, Jin L, Eisner-Smerage L, Taylor SJ, Rekosh D, Hammarskjold ML.Mol Cell Biol. 2003 Jan;23(1):92-103.
- 3.
- Purification and spectroscopic characterization of the human protein tyrosine kinase-6 SH3 domain.
Koo BK, Kim MH, Lee ST, Lee W.J Biochem Mol Biol. 2002 May 31;35(3):343-7.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PTK6 polyclonal antibody (Cat # PAB3434) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 5753
- Protein Accession#:
- Q13882
- Gene Name:
- PTK6
- Gene Alias:
- BRK,FLJ42088
- Gene Description:
- PTK6 protein tyrosine kinase 6
- Omim ID:
- 602004
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. [provided by RefSeq
- Other Designations:
- OTTHUMP00000031656,breast tumor kinase,protein-tyrosine kinase BRK
- Related Disease