CHST12,碳水化合物磺基转移酶12抗体

产品编号HZ-13931R
英文名称CHST12
中文名称碳水化合物磺基转移酶12抗体
别 名C4S 2; C4S2; C4ST 2; C4ST2; Carbohydrate (chondroitin 4) sulfotransferase 12; Chondroitin 4 O sulfotransferase 2; Chondroitin 4 sulfotransferase 2; Sulfotransferase Hlo; CHSTC_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 新陈代谢 细胞外基质
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,
CHST12,碳水化合物磺基转移酶12抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
细胞定位细胞膜 细胞外基质
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CHST12
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CHST12,碳水化合物磺基转移酶12抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]

Function:
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Subcellular Location:
Golgi apparatus membrane; Single pass type II membrane protein

Tissue Specificity:
Widely expressed. Expressed a high level in spinal chord, heart, spleen, thyroid, pituitary gland, adrenal gland, peripheral blood leukocytes, thymus, lung, small intestine, fetal kidney, fetal spleen and fetal lung.

Post-translational modifications:

Similarity:
Belongs to the sulfotransferase 2 family.

Gene ID:
55501

Database links:
Entrez Gene: 55501 Human
Omim: 610129 Human
SwissProt: Q9NRB3 Human
Unigene: 213088 Human

CHST12,碳水化合物磺基转移酶12抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.