HNMT (Human) Recombinant Protein (Q01)
产品名称： HNMT (Human) Recombinant Protein (Q01)
英文名称： HNMT (Human) Recombinant Protein (Q01)
产品编号： H00003176-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human HNMT partial ORF ( NP_008826, 184 a.a. - 292 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- KKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
- Theoretical MW (kDa):
- 37.73
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 3176
- GeneBank Accession#:
- NM_006895
- Protein Accession#:
- NP_008826
- Gene Name:
- HNMT
- Gene Alias:
- HMT,HNMT-S1,HNMT-S2
- Gene Description:
- histamine N-methyltransferase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq
- Other Designations:
- -
- Gene Pathway
- Related Disease
- Alcoholism
- Angioneurotic Edema
- Asthma
- Asthma
- Attention Deficit Disorder with Hyperactivity
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Chronic Disease
- Cognition
- Colitis, Ulcerative
- Dermatitis, Atopic
- Disease Progression
- Duodenal Ulcer
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Hearing Loss
- Hypercholesterolemia
- Hypersensitivity, Immediate