Anti-GPR24抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-GPR24抗体

Anti-GPR24抗体

商家询价

产品名称: Anti-GPR24抗体

英文名称: GPR24

产品编号: YB--10790R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-GPR24抗体

产品编号 YB-10790R
英文名称 GPR24
中文名称 G蛋白偶联受体24抗体
别    名 MCHR; G protein coupled receptor 24; GPCR MCH1; GPCR SLC/MCH1; MCH receptor 1; MCH1R; Melanin concentrating hormone receptor 1; SLC-1; Somatostatin receptor like protein; MCHR1_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR24:2-100/422 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
MCHR, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR does not seem to bind somatostatin.

Function:
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.

Subunit:
Interacts with NCDN.

Subcellular Location:
Cell Membrane; multi-pass membrane protein

Tissue Specificity:
Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.

Similarity:
Belongs to the G-protein coupled receptor 1 family. 

SWISS:
Q99705

Gene ID:
2847

Database links:

Entrez Gene: 2847 Human

Entrez Gene: 207911 Mouse

Entrez Gene: 83567 Rat

Omim: 601751 Human

SwissProt: Q99705 Human

SwissProt: Q8JZL2 Mouse

SwissProt: P97639 Rat

Unigene: 248122 Human

Unigene: 323523 Mouse

Unigene: 10822 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications