FITC标记的LRIT1蛋白抗体
产品名称： FITC标记的LRIT1蛋白抗体
英文名称： Anti-LRIT1/FITC
产品编号： HZ-18358R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LRIT1/FITC Conjugated antibody
FITC标记的LRIT1蛋白抗体
| 英文名称 | Anti-LRIT1/FITC |
| 中文名称 | FITC标记的LRIT1蛋白抗体 |
| 别 名 | DKFZP434K091; Fibronectin type III, immunoglobulin and leucine rich repeat domains 9; FIGLER9; immunoglobulin-like domain and transmembrane domain-containing protein 1; Leucine-rich repeat; Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1; Leucine-rich repeat-containing protein 21; Lrit1; LRIT1_HUMAN; LRRC21; PAL; Photoreceptor-associated LRR superfamily protein; Retina-specific protein PAL. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 66kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRIT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 21 (LRRC21), also designated leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1) or PAL, is a 623 amino acid protein that contains 6 LRR repeats. LRRC21 is expressed in retina and may play a role in phototransduction. Function: Possible role in phototransduction. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Contains 1 fibronectin type-III domain. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 26103 Human SwissProt: Q9P2V4 Human Unigene: 226000 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
富含亮氨酸（LRR）的重复序列是20-30个氨基酸基序，形成疏水的_/马蹄形折叠，允许其在紧密包装的核心内容纳几个亮氨酸残基。所有LRR重复序列都包含一个可变片段和一个高度保守的片段，后者占整个LRR基序的11或12个残基。这些基序的主要功能是提供一个多功能的结构框架来介导蛋白质-蛋白质相互作用的形成。LRR存在于多种结构和功能多样的蛋白质中，包括先天免疫和神经系统发育。一些人类疾病与编码含有LRR蛋白的基因的突变有关。富含亮氨酸的重复序列蛋白21(LRRC21)，也称为富含亮氨酸的重复序列、免疫球蛋白样结构域和跨膜结构域蛋白1(LRIT1)或PAL，是含有6个LRR重复序列的623个氨基酸蛋白。LRRC21在视网膜中表达，可能在光传导中起作用。