NDRG4 monoclonal antibody (M01), clone 2G3
产品名称： NDRG4 monoclonal antibody (M01), clone 2G3
英文名称： NDRG4 monoclonal antibody (M01), clone 2G3
产品编号： H00065009-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant NDRG4.
- Immunogen:
- NDRG4 (AAH11795.1, 1 a.a. ~ 339 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MPECWDGEHDIETPYGLLHVVIRGSPKGNRPAILTYHDVGLNHKLCFNTFFNFEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPSMEQLAAMLPSVVQHFGFKYVIGIGVGAGAYVLAKFALIFPDLVEGLVLVNIDPNGKGWIDWAATKLSGLTSTLPDTVLSHLFSQEELVNNTELVQSYRQQIGNVVNQANLQLFWNMYNSRRDLDINRPGTVPNAKTLRCPVMLVVGDNAPAEDGVVECNSKLDPTTTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSASSVDGSRPQACTHSESSEGLGQVNHTMEVSC
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Isotype:
- IgG1 kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (63.03 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- NDRG4 is Downregulated in Glioblastoma and Inhibits Cell Proliferation.
Ding W, Zhang J, Yoon JG, Shi D, Foltz G, Lin B.OMICS. 2012 May;16(5):263-7. Epub 2012 Apr 10.
- 2.
- N-Myc Downstream-Regulated Gene 4 (NDRG4): A Candidate Tumor Suppressor Gene and Potential Biomarker for Colorectal Cancer.
Melotte V, Lentjes MH, van den Bosch SM, Hellebrekers DM, de Hoon JP, Wouters KA, Daenen KL, Partouns-Hendriks IE, Stessels F, Louwagie J, Smits KM, Weijenberg MP, Sanduleanu S, Khalid-de Bakker CA, Oort FA, Meijer GA, Jonkers DM, Herman JG, de Bruine AP,J Natl Cancer Inst. 2009 Jul 1;101(13):916-27. Epub 2009 Jun 17.
- 3.
- Identification and action of N-myc downstream regulated gene 4 A2 in rat pancreas.
Wang JF, Hill DJ.J Endocrinol. 2009 Apr;201(1):15-25. Epub 2009 Feb 4.
- Applications
- Western Blot (Cell lysate)
- NDRG4 monoclonal antibody (M01), clone 2G3. Western Blot analysis of NDRG4 expression in Raw 264.7.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to NDRG4 on formalin-fixed paraffin-embedded human colon adenocarcinoma. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged NDRG4 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 65009
- GeneBank Accession#:
- BC011795
- Protein Accession#:
- AAH11795.1
- Gene Name:
- NDRG4
- Gene Alias:
- DKFZp686I1615,FLJ30586,FLJ42011,KIAA1180,MGC19632,SMAP-8
- Gene Description:
- NDRG family member 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
- Other Designations:
- smooth muscle-associated protein 8