FITC标记的丝氨酸蛋白酶35抗体
产品名称： FITC标记的丝氨酸蛋白酶35抗体
英文名称： Anti-PRSS35/FITC
产品编号： HZ-19440R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PRSS35/FITC Conjugated antibody
FITC标记的丝氨酸蛋白酶35抗体
| 英文名称 | Anti-PRSS35/FITC |
| 中文名称 | FITC标记的丝氨酸蛋白酶35抗体 |
| 别 名 | 6030424L22Rik; C6orf158; Inactive serine protease 35; MGC46520; P3D9; protease, serine, 35; PRSS 35. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRSS35 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PRSS35, although related to the peptidase S1 family, lacks the conserved active Ser residue in position 346 which is replaced by a Thr, suggesting that it has no protease activity. This Ser to Thr substitution may play an important role in determining a unique pattern of substrate specificity for PRSS35. Alternatively, this substitution may yield an inactive protease that binds to specific substrates, thus protecting them from proteolysis. The Mouse Prss35 gene is selectively expressed in the ovary and it's expression prior to ovulation is, in part, regulated by progesterone. PRSS35 may be involved in ovulation and the formation and regression of the corpus luteum. Subcellular Location: Secreted Database links: Entrez Gene: 167681 Human Entrez Gene: 244954 Mouse Entrez Gene: 315866 Rat SwissProt: Q8N3Z0 Human SwissProt: Q8C0F9 Mouse SwissProt: Q5R212 Rat Unigene: 98381 Human Unigene: 257629 Mouse Unigene: 161916 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
PRSS35虽然与肽酶S1家族有关，但在位置346缺少保守的活性Ser残基，被Thr取代，表明它没有蛋白酶活性。这种SER到THR替代可能在确定PrSS35的底物特异性的独特模式中起重要作用。或者，这种取代可以产生与特定底物结合的非活性蛋白酶，从而保护它们免于蛋白水解。小鼠Prss35基因在卵巢中选择性表达，其在排卵前的表达部分受孕酮调节。PRSS35可能参与排卵和黄体的形成和退化。