GSTA2 (Human) Recombinant Protein (Q01)
产品名称: GSTA2 (Human) Recombinant Protein (Q01)
英文名称: GSTA2 (Human) Recombinant Protein (Q01)
产品编号: H00002939-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GSTA2 partial ORF ( AAH02895, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIA
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2939
- GeneBank Accession#:
- BC002895
- Protein Accession#:
- AAH02895
- Gene Name:
- GSTA2
- Gene Alias:
- GST2,GSTA2-2,GTA2,GTH2,MGC10525
- Gene Description:
- glutathione S-transferase alpha 2
- Omim ID:
- 138360
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq
- Other Designations:
- GST, class alpha, 2,GST-gamma,HA subunit 2,OTTHUMP00000017883,S-(hydroxyalkyl)glutathione lyase A2,glutathione S-alkyltransferase A2,glutathione S-aralkyltransferase A2,glutathione S-aryltransferase A2,glutathione S-transferase 2,glutathione S-transferase
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Cognition
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Laryngeal Neoplasms
- Lung Neoplasms
- Mesothelioma
- Mouth Neoplasms