AICDA polyclonal antibody
产品名称： AICDA polyclonal antibody
英文名称： AICDA polyclonal antibody
产品编号： PAB7460
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of AICDA.
- Immunogen:
- A synthetic peptide corresponding to human AICDA.
- Sequence:
- RRKFLYQFKNVR-C
- Host:
- Goat
- Theoretical MW (kDa):
- 24
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Regulation of AID expression in the immune response.
Crouch EE, Li Z, Takizawa M, Fichtner-Feigl S, Gourzi P, Montano C, Feigenbaum L, Wilson P, Janz S, Papavasiliou FN, Casellas R.J Exp Med. 2007 May 14;204(5):1145-56. Epub 2007 Apr 23.
- Entrez GeneID:
- 57379
- Protein Accession#:
- NP_065712.1
- Gene Name:
- AICDA
- Gene Alias:
- AID,ARP2,CDA2,HIGM2
- Gene Description:
- activation-induced cytidine deaminase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq
- Other Designations:
- activation-induced deaminase,integrated into Burkitt's lymphoma cell line Ramos
- Gene Pathway
- Related Disease
- Asthma
- Asthma
- Bronchial Hyperreactivity
- Gastritis, Atrophic
- Genetic Predisposition to Disease
- Helicobacter Infections
- Hematologic Diseases
- Hodgkin Disease
- Hypersensitivity, Immediate
- Immunologic Deficiency Syndromes
- Kidney Failure, Chronic
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoproliferative Disorders
- Occupational Diseases
- Severe Combined Immunodeficiency
- Stomach Neoplasms
- Tobacco Use Disorder