PIK3R2 (C-term) Peptide
产品名称： PIK3R2 (C-term) Peptide
英文名称： PIK3R2 (C-term) Peptide
产品编号： P3004
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PIK3R2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PIK3R2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme.
Janssen JW, Schleithoff L, Bartram CR, Schulz AS.Oncogene. 1998 Apr 2;16(13):1767-72.
- 2.
- Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta.
Volinia S, Patracchini P, Otsu M, Hiles I, Gout I, Calzolari E, Bernardi F, Rooke L, Waterfield MD.Oncogene. 1992 Apr;7(4):789-93.
- 3.
- Purification and characterization of phosphoinositide 3-kinase from rat liver.
Carpenter CL, Duckworth BC, Auger KR, Cohen B, Schaffhausen BS, Cantley LC.J Biol Chem. 1990 Nov 15;265(32):19704-11.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of PIK3R2 polyclonal antibody (Cat # PAB3222) in A-549 cell lysate. PIK3R2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PIK3R2 polyclonal antibody (Cat # PAB3222) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 5296
- Protein Accession#:
- O00459
- Gene Name:
- PIK3R2
- Gene Alias:
- P85B,p85,p85-BETA
- Gene Description:
- phosphoinositide-3-kinase, regulatory subunit 2 (beta)
- Omim ID:
- 603157
- Gene Ontology:
- Hyperlink
- Other Designations:
- phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta),phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta),phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
- Gene Pathway
- Acute myeloid leukemia
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Glioma
- Insulin signaling pathway
- Jak-STAT signaling pathway
- Leukocyte transendothelial migration
- Melanoma
- mTOR signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Phosphatidylinositol signaling system
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Small cell lung cancer
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- VEGF signaling pathway