AIB1/CEN20q FISH Probe
产品名称: AIB1/CEN20q FISH Probe
英文名称: AIB1/CEN20q FISH Probe
产品编号: FG0034
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
Hybridization position of the probes on the chromosome.-
- Probe 1:
Size:
Fluorophore:
Location: - AIB1
Approximately 350kb
Texas Red
20q12
- Probe 2:
Size:
Fluorophore:
Location: - CEN20q
Approximately 680kb
FITC
20q11.22
- Probe Gap:
- The gap between two probes is approximately 9,300 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human breast cancer (FFPE) stained with AIB1/CEN20q FISH Probe. Human breast cancer showed no AIB1 gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 8202
- Gene Name:
- NCOA3
- Gene Alias:
- ACTR,AIB-1,AIB1,CAGH16,CTG26,KAT13B,MGC141848,RAC3,SRC3,TNRC14,TNRC16,TRAM-1,bHLHe42,pCIP
- Gene Description:
- nuclear receptor coactivator 3
- Omim ID:
- 601937
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq
- Other Designations:
- CBP-interacting protein,OTTHUMP00000031716,OTTHUMP00000031718,amplified in breast cancer-1,receptor-associated coactivator 3,steroid receptor coactivator protein 3,thyroid hormone receptor activator molecule 1
- Related Disease
- Alcoholism
- Body Weight
- Breast cancer
- Breast Neoplasms
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Edema
- Endometrial Neoplasms
- Genetic Predisposition to Disease
- Interview, Psychological
- Lung Neoplasms
- Lymphoma, Non-Hodgkin
- Neoplasm Recurrence, Local
- Neoplasms, Glandular and Epithelial
- Obesity
- Obesity
- Ovarian cancer
- Ovarian Neoplasms
- Prostate cancer