PAX5 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： PAX5 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： PAX5 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00005079-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human PAX5 protein.
- Immunogen:
- PAX5 (NP_057953.1, 1 a.a. ~ 391 a.a) full-length human protein.
- Sequence:
- MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of PAX5 expression in transfected 293T cell line (H00005079-T01) by PAX5 MaxPab polyclonal antibody.
Lane 1: PAX5 transfected lysate(42.10 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 5079
- GeneBank Accession#:
- NM_016734.1
- Protein Accession#:
- NP_057953.1
- Gene Name:
- PAX5
- Gene Alias:
- BSAP
- Gene Description:
- paired box 5
- Omim ID:
- 167414
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq
- Other Designations:
- B-cell lineage specific activator,paired box homeotic gene 5,transcription factor PAX 5
- Related Disease