FITC标记的半乳糖神经酰胺磺基转移酶抗体
产品名称： FITC标记的半乳糖神经酰胺磺基转移酶抗体
英文名称： Anti-GAL3ST1/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GAL3ST1/FITC Conjugated antibody
FITC标记的半乳糖神经酰胺磺基转移酶抗体
| 英文名称 | Anti-GAL3ST1/FITC |
| 中文名称 | FITC标记的半乳糖神经酰胺磺基转移酶抗体 |
| 别 名 | 3' phosphoadenosine 5' phosphosulfate:GalCer sulfotransferase; 3' phosphoadenylylsulfate:galactosylceramide 3' sulfotransferase; 3''-phosphoadenosine-5''-phosphosulfate:GalCer sulfotransferase; 3''-phosphoadenylylsulfate:galactosylceramide 3''-sulfotransferase; Cerebroside (3' phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase; Cerebroside sulfotransferase; CST; G3ST1_HUMAN; GAL3ST1; Galactose 3 O sulfotransferase 1; Galactosylceramide sulfotransferase; GalCer sulfotransferase. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GAL3ST1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008] Function: Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes (By similarity). Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro). Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in kidney proximal tubule, gastric mucosa and adenocarcinoma. Highly expressed in renal cell carcinoma cell lines. Similarity: Belongs to the galactose-3-O-sulfotransferase family. Database links: Entrez Gene: 9514 Human Omim: 602300 Human SwissProt: Q99999 Human Unigene: 17958 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
磺化是许多药物、外源生物、和神经递质代谢的重要步骤，它由磺基转移酶催化。该基因的产物是半乳糖基神经酰胺硫转移酶，催化3’-磷酸腺苷酰基硫酸酯+半乳糖基神经酰胺向3’，5’-二磷酸腺苷+半乳糖基神经酰胺硫酸酯的转化。这种转移酶活性在肾细胞癌中增强。[ RefSeq，JUL 2008 ]