甘丙肽受体拮抗剂抗体
产品名称: 甘丙肽受体拮抗剂抗体
英文名称: Galantide
产品编号: hz-16216R
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ELISA=1:500-1000
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Rabbit Anti-Galantide antibody
产品编号 | hz-16216R |
英文名称 | Galantide |
中文名称 | 甘丙肽受体拮抗剂抗体 |
别 名 | Galanin receptor antagonist; Reversible galanin receptor antagonist; M15. |
产品类型 | 药物与化合物抗体 |
研究领域 | 神经生物学 信号转导 通道蛋白 G蛋白偶联受体 G蛋白信号 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | ELISA=1:500-1000 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 2kDa |
细胞定位 | 分泌型蛋白 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide of Galantide:1-20/20 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: The galanin antagonist Galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C terminal fragment of bradykinin, has been found to improve social memory in `social recognition' tests when i.c.v. administered at doses varying from 6-6000 nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose induced insulin secretion. Subcellular Location: Secreted. Database links:
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |