FITC标记的骨诱导因子抗体
产品名称： FITC标记的骨诱导因子抗体
英文名称： Anti-OIF/FITC
产品编号： HZ-9407R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-OIF/FITC Conjugated antibody
FITC标记的骨诱导因子抗体
| 产品编号 | bs-9407R-FITC |
| 英文名称 | Anti-OIF/FITC |
| 中文名称 | FITC标记的骨诱导因子抗体 |
| 别 名 | Corneal keratan sulfate proteoglycan; MIME_HUMAN; mimecan; Mimecan proteoglycan; OG; OGN; OIF; osteoglycin; osteoinductive factor; SLRR3A. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞分化 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OIF |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGF beta. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TGF-beta-1 or TGF-beta-2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin. Function: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. Subcellular Location: Secreted, extracellular space, extracellular matrix. Tissue Specificity: Bone. Post-translational modifications: N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. Similarity: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. Contains 7 LRR (leucine-rich) repeats. Database links: Entrez Gene: 4969 Human Omim: 602383 Human SwissProt: P20774 Human Unigene: 109439 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
富含亮氨酸的蛋白多糖（SLRP）家族含有多种蛋白质，如Decorin、二聚糖、纤维性调节蛋白、角蛋白、LuMiCa、Osteoadherin和Osteoglycin。这些蛋白都具有类似的功能，因为它们都介导细胞外基质的组织，并作为TGF-β的结合伙伴。骨糖蛋白，也可被称为骨诱导因子（OIF），是在骨组织中检测到的分泌蛋白。骨糖蛋白结合TGF-β1或TGF-β-2诱导骨形成。OGN基因产物的前体形式，命名为Mimecan，受原位蛋白水解切割，以产生成熟的骨糖蛋白。