CD14 (N-term) Peptide
产品名称： CD14 (N-term) Peptide
英文名称： CD14 (N-term) Peptide
产品编号： P1916
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CD14.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CD14.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Local expression of interleukin-10 and mCD14 in relation to the -1087 IL-10 and -159 CD14 gene polymorphisms in chronic periodontitis.
Donati M, Liljenberg B, Padyukov L, Berglundh T.J Periodontol. 2008 Mar;79(3):517-24.
- 2.
- Clinical relevance of TLR2, TLR4, CD14 and FcgammaRIIA gene polymorphisms in Streptococcus pneumoniae infection.
Yuan FF, Marks K, Wong M, Watson S, de Leon E, McIntyre PB, Sullivan JS.Immunol Cell Biol. 2008 Mar-Apr;86(3):268-70. Epub 2008 Jan 8.
- 3.
- Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones.
Setoguchi M, Nasu N, Yoshida S, Higuchi Y, Akizuki S, Yamamoto S.Biochim Biophys Acta. 1989 Jul 7;1008(2):213-22.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of CD14 (arrow) using rabbit CD14 polyclonal antibody (Cat # PAB4880). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CD14 gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CD14 polyclonal antibody (Cat # PAB4880) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Entrez GeneID:
- 929
- Protein Accession#:
- NP_000582;P08571
- Gene Name:
- CD14
- Gene Alias:
- -
- Gene Description:
- CD14 molecule
- Omim ID:
- 158120
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq
- Other Designations:
- CD14 antigen,monocyte differentiation antigen CD14
- Related Disease
- Abortion, Habitual
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- Adenocarcinoma
- Aggressive Periodontitis
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- Alcoholism
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Anaphylaxis
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- Arthritis, Reactive