FITC标记的BCL2样10促凋亡蛋白抗体
产品名称： FITC标记的BCL2样10促凋亡蛋白抗体
英文名称： Anti-BCL2L10/FITC
产品编号： HZ-5796R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BCL2L10/FITC Conjugated antibody
FITC标记的BCL2样10促凋亡蛋白抗体
| 英文名称 | Anti-BCL2L10/FITC |
| 中文名称 | FITC标记的BCL2样10促凋亡蛋白抗体 |
| 别 名 | Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10 (apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BCL2L10 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Function: Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. Subunit: Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. Subcellular Location: Mitochondrion. Nucleus membrane. Tissue Specificity: Widely expressed in adult tissues. Similarity: Belongs to the Bcl-2 family. Database links: Entrez Gene: 10017 Human Omim: 606910 Human SwissProt: Q9HD36 Human Unigene: 283672 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Bcl-2家族成员通过抑制或促进细胞死亡是细胞凋亡的关键调节因子。BCL2L10是最近发现的抗凋亡细胞Bcl-2。不同于小鼠同源物（也称为DIVA/BOO），其主要在卵巢和睾丸中表达，人类BCL2L10蛋白被广泛表达。此外，人BC2L10通过结合和抑制Bax的凋亡活性而起作用，而小鼠同源物结合BAK，并且还与凋亡蛋白APAF-1相互作用。