Anti-HSD3B1+ HSD3B2抗体
产品名称： Anti-HSD3B1+ HSD3B2抗体
英文名称： HSD3B1+ HSD3B2
产品编号： YB--16551R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-HSD3B1+ HSD3B2抗体
| 产品编号 | YB-16551R |
| 英文名称 | HSD3B1+ HSD3B2 |
| 中文名称 | 滋养层细胞抗原3β-HSD抗体 |
| 别 名 | 3 beta and steroid delta isomerase 1; 3 beta and steroid hydroxy delta 5 steroid dehydrogenase; 3 beta HSD I; 3BH; 3BHSD; HGNC:5217; HSD3B; HSD3B1; HSDB3; HSDB3A; Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1; Hydroxy delta 5 steroid dehydrogenase; trophoblast antigen; 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; Short=3-beta-HSD I; Trophoblast antigen FDO161G; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; 3-beta-hydroxy-5-ene steroid dehydrogenase; Progesterone reductase; Steroid Delta-isomerase; Delta-5-3-ketosteroid isomerase. |
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSD3B1+ HSD3B2:101-200/372 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Tissue Specificity: Placenta and skin. Predominantly expressed in mammary gland tissue. Similarity: Belongs to the 3-beta-HSD family. SWISS: P14060 Gene ID: 3283 Database links: Entrez Gene: 3283 Human Entrez Gene: 3284 Human Entrez Gene: 15492 Mouse Entrez Gene: 15494 Mouse Entrez Gene: 29632 Rat Entrez Gene: 360348 Rat Entrez Gene: 682974 Rat Omim: 109715 Human SwissProt: P14060 Human SwissProt: P26439 Human SwissProt: O35469 Mouse SwissProt: P24815 Mouse SwissProt: P26149 Mouse SwissProt: P26150 Mouse SwissProt: P22071 Rat SwissProt: P22072 Rat SwissProt: Q5FVK0 Rat SwissProt: Q62878 Rat Unigene: 364941 Human Unigene: 654399 Human Unigene: 140811 Mouse Unigene: 14435 Mouse Unigene: 158717 Mouse Unigene: 482364 Mouse Unigene: 109394 Rat Unigene: 128814 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HSD3B1属于滋养层细胞标记物（也包括hPL、hCG、Mel-CAN、p63、HLA—G、CK18和inhibin-α） 在很多肿瘤及正常内分泌组织中表达也很高 |
| 产品图片 |
 Sample:
Adrenal gland (Mouse) Lysate at 40 ug Primary: Anti-HSD3B1+ HSD3B2 (bs-16551R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 41 kD |