Anti-Involucrin/FITC Conjugated抗体
产品名称： Anti-Involucrin/FITC Conjugated抗体
英文名称： Anti-Involucrin/FITC
产品编号： YB--1236R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
上海钰博生物科技有限公司
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Anti-Involucrin/FITC Conjugated抗体
| 产品编号 | YB-1236R-FITC |
| 英文名称 | Anti-Involucrin/FITC |
| 中文名称 | FITC标记的囊包蛋白/内披蛋白抗体 |
| 别 名 | INVO_HUMAN; involucrin; ivl. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 64kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Involucrin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]. Function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Subunit: Directly or indirectly cross-linked to cornifelin (CNFN). Subcellular Location: Cytoplasm. Tissue Specificity: Keratinocytes of epidermis and other stratified squamous epithelia. Post-translational modifications: Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. Similarity: Belongs to the involucrin family. Database links: Entrez Gene: 3713 Human Entrez Gene: 16447 Mouse Entrez Gene: 60583 Rat Omim: 147360 Human SwissProt: P07476 Human SwissProt: P48997 Mouse SwissProt: P48998 Rat Unigene: 516439 Human Unigene: 207365 Mouse Unigene: 142591 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 套膜蛋白又称内披蛋白或囊包蛋白，与毛透明蛋白共同构成角质细胞包膜支架的蛋白质。在角质细胞分化时，首先出现在表皮棘层的上层细胞中的标志性蛋白质，该蛋白在角质细胞和其他复层扁平上皮合成的蛋白。最初存在于细胞质中，然后通过转谷氨酰胺酶的作用，转变为交联的膜蛋白 |