FITC标记的Bcl-2结合抑凋亡蛋白2抗体
产品名称： FITC标记的Bcl-2结合抑凋亡蛋白2抗体
英文名称： Anti-BAG2/FITC
产品编号： HZ-5134R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-BAG2/FITC Conjugated antibody
FITC标记的Bcl-2结合抑凋亡蛋白2抗体
| 英文名称 | Anti-BAG2/FITC |
| 中文名称 | FITC标记的Bcl-2结合抑凋亡蛋白2抗体 |
| 别 名 | BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC149462. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BAG2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Similarity: Contains 1 BAG domain. Database links: Entrez Gene: 9532 Human Omim: 603882 Human SwissProt: O95816 Human Unigene: 55220 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
袋蛋白与HIP竞争结合HSC70/HSP70 ATPase结构域，促进底物释放。所有袋蛋白在C端附近具有大约45个氨基酸袋域，但在它们的N-末端区明显不同。预测的BAG2蛋白含有211个氨基酸。BAG1、BAG2和BAG3的包结构域与HSC70 ATPase结构域在体外和哺乳动物细胞中特异性地相互作用。所有3种蛋白与HSC70 ATPase结构域具有高度亲和性，并以HIP抑制方式抑制其伴侣活性。[由RefSeq提供]。