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上海信裕生物科技有限公司
CAPG抗体

CAPG抗体

商家询价

产品名称: CAPG抗体

英文名称: CAPGAntibody

产品编号: XY10194-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 CAPG抗体

Applications
In-house applications ELISA, WB, IHC, IF, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 10 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev12NextView more validation data
  • 10194-1-AP;HeLa cellHeLa cells were subjected to SDS PAGE followed by western blot with 10194-1-AP(CAPG antibody) at dilution of 1:1000
  • 10194-1-AP;Prostate cancerImmunohistochemical of paraffin-embedded human prostate cancer using 10194-1-AP(CAPG antibody) at dilution of 1:100 (under 10x lens)
  • 10194-1-AP;MCF-7Immunofluorescent analysis of MCF-7 cells, using CAPG antibody 10194-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
  • 10194-1-AP;mouse heart tissueIP Result of anti-CAPG (IP:10194-1-AP, 4ug; Detection:10194-1-AP 1:500) with mouse heart tissue lysate 4000ug.
Positive WB detected in HeLa cells, HL-60 cells, mouse heart tissue, mouse thymus tissue, rat heart tissue, rat lung tissue
Positive IP detected in Mouse heart tissue
Positive IHC detected in Human prostate cancer tissue, human tonsillitis tissue
Positive IF detected in MCF-7 cells
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200
 CAPG抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CAPG fusion protein ag0248 Full name Capping protein (actin filament), gelsolin-like
Calculated molecular
weight
39 kDa Observed molecular 
weight
39-42kd
GenBank accession 
number
BC000728 Gene ID (NCBI) 822
Gene symbol CAPG Synonyms Actin regulatory protein CAP G, AFCP, CAPG, Macrophage capping protein, MCP
Background CAPG抗体

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129) CAPG抗体

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