IL5 monoclonal antibody, clone JES1-5A10 (Biotin)
产品名称： IL5 monoclonal antibody, clone JES1-5A10 (Biotin)
英文名称： IL5 monoclonal antibody, clone JES1-5A10 (Biotin)
产品编号： MAB5869
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rat monoclonal antibody raised against recombinant IL5.
- Immunogen:
- Recombinant protein corresponding to human IL5.
- Host:
- Rat
- Reactivity:
- Human
- Specificity:
- human Interleukin-5 (IL-4)1-4.
- Form:
- Liquid
- Conjugation:
- Biotin
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS (0.5 mg/mL sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.Immunol Rev. 1992 Jun;127:5-24.
- 2.
- Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis.
Limaye AP, Abrams JS, Silver JE, Awadzi K, Francis HF, Ottesen EA, Nutman TB.J Clin Invest. 1991 Oct;88(4):1418-21.
- 3.
- Interleukin-5 is a human basophilopoietin: induction of histamine content and basophilic differentiation of HL-60 cells and of peripheral blood basophil-eosinophil progenitors.
Denburg JA, Silver JE, Abrams JS.Blood. 1991 Apr 1;77(7):1462-8.
- Application Image
- Sandwich ELISA
- Entrez GeneID:
- 3567
- Gene Name:
- IL5
- Gene Alias:
- EDF,IL-5,TRF
- Gene Description:
- interleukin 5 (colony-stimulating factor, eosinophil)
- Omim ID:
- 147850
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq
- Other Designations:
- B cell differentiation factor I,OTTHUMP00000065830,T-cell replacing factor,eosinophil differentiation factor,interleukin 5,interleukin-5
- Related Disease
- Adenocarcinoma
- Asthma
- Asthma
- Bacteremia
- Biliary Tract Neoplasms
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Celiac Disease
- Chorioamnionitis
- Colitis, Ulcerative
- Connective Tissue Diseases
- Crohn Disease
- Crohn's disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Ductus Arteriosus, Patent