FITC标记的ATP结合盒蛋白家族GCN20F家族1抗体
产品名称： FITC标记的ATP结合盒蛋白家族GCN20F家族1抗体
英文名称： Anti-ABCF1/FITC
产品编号： HZ-1960R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-ABCF1/FITC Conjugated antibody
FITC标记的ATP结合盒蛋白家族GCN20F家族1抗体
| 英文名称 | Anti-ABCF1/FITC |
| 中文名称 | FITC标记的ATP结合盒蛋白家族GCN20F家族1抗体 |
| 别 名 | ATP-binding cassette sub-family F (GCN20) member 1; Abc50; GCN20; AU041969; D17Wsu166e; Abcf1; ABC27; ATP binding cassette 50 (TNF alpha stimulated); ATP binding cassette 50; ATP binding cassette sub family F member 1; EST123147; TNF alpha stimulated ABC protein; TNFalpha inducible ATP binding protein; wu:fb79c06; wu:fc39a05; wu:fj94a08; zgc:85667; ABCF1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 染色质和核信号 信号转导 结合蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 96kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ABCF1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008] Function: Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. Subunit: Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes. Subcellular Location: Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope. Tissue Specificity: Ubiquitous. Post-translational modifications: Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes. Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. Contains 2 ABC transporter domains. Database links: Entrez Gene: 23 Human Entrez Gene: 224742 Mouse Entrez Gene: 100144452 Pig Omim: 603429 Human SwissProt: Q8NE71 Human SwissProt: Q6P542 Mouse SwissProt: Q767L0 Pig Unigene: 655285 Human Unigene: 329022 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是ATP结合盒（ABC）转运蛋白超家族的成员。ABC蛋白通过胞外膜和胞内膜运输各种分子。ABC基因分为七个不同亚家族（ABC1、MDR/TAP、MRP、ALD、OABP、GCN20、White）。这种蛋白是GCN20亚家族的成员。与超家族的其他成员不同，这种蛋白质缺乏跨膜结构域，这是大多数ABC转运蛋白的特征。该蛋白可通过肿瘤坏死因子α调节，并在蛋白质合成和炎症过程中发挥作用。[ RefSeq，JUL 2008 ]