FITC标记的γ-氨基丁酸醛脱氢酶抗体
产品名称： FITC标记的γ-氨基丁酸醛脱氢酶抗体
英文名称： Anti-ALDH9A1/FITC
产品编号： HZ-12461R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-ALDH9A1/FITC Conjugated antibody
FITC标记的γ-氨基丁酸醛脱氢酶抗体
| 英文名称 | Anti-ALDH9A1/FITC |
| 中文名称 | FITC标记的γ-氨基丁酸醛脱氢酶抗体 |
| 别 名 | 4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; ALDH4; ALDH7; ALDH9; aldh9A1; E3; Gamma aminobutyraldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; TMABADH. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ALDH9A1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction. Function: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Tissue Specificity: High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the aldehyde dehydrogenase family. Database links: Entrez Gene: 223 Human Entrez Gene: 56752 Mouse Entrez Gene: 64040 Rat Omim: 602733 Human SwissProt: P49189 Human SwissProt: Q9JLJ2 Mouse SwissProt: Q9JLJ3 Rat Unigene: 2533 Human Unigene: 330055 Mouse Unigene: 474999 Mouse Unigene: 98155 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
醛脱氢酶(ALDHs)介导NADP+依赖性的醛氧化成酸，在乙醇衍生乙醛的解毒以及脂质过氧化和皮质类固醇、生物胺和神经递质的代谢中起重要作用。ALDH9A1(醛脱氢酶家族9成员A1)，又称E3、ALDH4、ALDH7、ALDH9或TMABADH，是一种在成人肝脏、骨骼肌、肾脏和胚胎脑中高度表达的494氨基酸细胞质蛋白。ALDH9A1将γ-三甲基氨基丁醛转化为γ-丁基苯甲酸，并在NAD依赖的反应中催化大范围的醛不可逆氧化成相应的酸。