PCDHGB4,原钙粘蛋白γB4抗体

产品编号HZ-11157R
英文名称PCDHGB4
中文名称原钙粘蛋白γB4抗体
别 名Cadherin-20; Cadherin20; Cadherin 20; CDH20; FIB2; Fibroblast cadherin FIB2; Fibroblast cadherin-2; PCDGG_HUMAN; PCDH-gamma-B4; PCDHGB4; Protocadherin gamma subfamily B 4; Protocadherin gamma-B4.
说 明 书0.1ml 0.2ml
研究领域神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow,
PCDHGB4,原钙粘蛋白γB4抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量97kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human PCDHGB4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PCDHGB4,原钙粘蛋白γB4抗体PubMedPubMed
产品介绍background:
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-20, also known as protocadherin gamma B4, is a member of the protocadherin gamma gene cluster. Expressed primariy in fibroblasts, cadherin-20 plays a critical role in neuronal cell-cell connections in the brain. Through its ability to mediate cell-cell adhesion, caderin-20 is thought to help the body respond to injury by regulating post-traumatic wound healing.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subunit:
Contains 6 cadherin domains.

Subcellular Location:
Cell membrane.

Similarity:
Contains 6 cadherin domains.

Gene ID:
8641

Database links:
Entrez Gene: 8641 Human
Entrez Gene: 93701 Mouse
UniProtKB/Swiss-Prot: Q9UN71.1

PCDHGB4,原钙粘蛋白γB4抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.