COX7C,细胞色素C氧化酶蛋白7C抗体

产品编号HZ-14016R
英文名称COX7C
中文名称细胞色素C氧化酶蛋白7C抗体
别 名COX7C; COX7C_HUMAN; Cytochrome c oxidase polypeptide VIIc; Cytochrome c oxidase subunit 7C; mitochondrial.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
COX7C,细胞色素C氧化酶蛋白7C抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量6.2kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human COX7C
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
COX7C,细胞色素C氧化酶蛋白7C抗体PubMedPubMed
产品介绍background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Location:
Mitochondrion inner membrane.

Post-translational modifications:

DISEASE:

Similarity:
Belongs to the cytochrome c oxidase VIIc family.

Gene ID:
1350

Database links:
Entrez Gene: 1350 Human
Entrez Gene: 12867 Mouse
Entrez Gene: 100188937 Rat
Omim: 603774 Human
SwissProt: P15954 Human
SwissProt: P17665 Mouse
SwissProt: P80432 Rat
Unigene: 430075 Human
Unigene: 378898 Mouse
Unigene: 105968 Rat

COX7C,细胞色素C氧化酶蛋白7C抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.