SERPINB10,丝氨酸蛋白酶抑制剂B10抗体

产品编号HZ-9211R
英文名称SERPINB10
中文名称丝氨酸蛋白酶抑制剂B10抗体
别 名Bomapin; PI10; Protease inhibitor 10; Protease inhibitor 10 (ovalbumin type bomapin); Serpin B10; Serpin peptidase inhibitor clade B (ovalbumin) member 10; SPB10_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 细胞生物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human,
SERPINB10,丝氨酸蛋白酶抑制剂B10抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SERPINB10
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SERPINB10,丝氨酸蛋白酶抑制剂B10抗体PubMedPubMed
产品介绍background:
SERPINB10 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in human bone marrow in a search for serpins similar to SerpinB6. SERPINB10 was identified in lymphocytes, and was elevated in chronic myeloid leukemia and chronic myelomonocytic leukemia cells. The monocytic cell lines THP-1 and AML-193 also showed elevated SERPINB10 expression.

Function:
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Expressed specifically in the bone marrow.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

Gene ID:
5273

SERPINB10,丝氨酸蛋白酶抑制剂B10抗体Database links:
Entrez Gene: 5273 Human
GenBank: NP_005015.1 Human
Omim: 602058 Human
SwissProt: P48595 Human
SwissProt: Q4VAX7 Human
Unigene: 158339 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.