TNFRSF10A monoclonal antibody, clone HS101
产品名称: TNFRSF10A monoclonal antibody, clone HS101
英文名称: TNFRSF10A monoclonal antibody, clone HS101
产品编号: MAB3473
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant TNFRSF10A.
- Immunogen:
- Recombinant protein corresponding to human TNFRSF10A.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3, or -R4.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ug/mL)
The optimal working dilution should be determined by the end user.
- Applications
- Flow Cytometry
- Flow cytometric detection of endogenous TNFRSF10A. BJAB cells (1 X 106) were stained with TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473) (Black histogram) or with an unspecified mouse IgG1 antibody as a control (white histogram).
- Flow Cytometry
- Receptor specificity of the TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473). CV1/EBNA cells were transfected either with the empty expression vector pCDNA3 (vector control) or pCDNA3 encoding TNFRSF10A to TNFRSF10D. Two days after transfection, 1 X 106 cells were stained with TNFRSF10A monoclonal antibody, clone HS101 (Cat # MAB3473).
- Entrez GeneID:
- 8797
- Gene Name:
- TNFRSF10A
- Gene Alias:
- APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1
- Gene Description:
- tumor necrosis factor receptor superfamily, member 10a
- Omim ID:
- 603611
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq
- Other Designations:
- TNF-related apoptosis inducing ligand receptor 1,cytotoxic TRAIL receptor,death receptor 4
- Related Disease
- Adenocarcinoma
- Asthma
- Atherosclerosis
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Cardiovascular Diseases
- Colorectal Neoplasms
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Lung Neoplasms
- Lymphatic Metastasis
- Lymphoma, Large B-Cell, Diffuse
- Lymphoproliferative Disorders