PIK3CA/CEN3q FISH Probe
产品名称: PIK3CA/CEN3q FISH Probe
英文名称: PIK3CA/CEN3q FISH Probe
产品编号: FG0073
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - PIK3CA
Approximately 280kb
Texas Red
3q26.32
- Probe 2:
Size:
Fluorophore:
Location: - CEN3q
Approximately 500kb
FITC
3q12.1
- Probe Gap:
- The gap between two probes is approximately 82,800 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human lung adenosquamous cell carcinoma (FFPE) stained with PIK3CA/CEN3q FISH Probe. Human lung adenosquamous cell carcinoma showed PIK3CA gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 5290
- Gene Name:
- PIK3CA
- Gene Alias:
- MGC142161,MGC142163,PI3K,p110-alpha
- Gene Description:
- phosphoinositide-3-kinase, catalytic, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq
- Other Designations:
- PI3-kinase p110 subunit alpha,PtdIns-3-kinase p110,phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha,phosphatidylinositol 3-kinase, catalytic, alpha polypeptide,phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform
- Gene Pathway
- Acute myeloid leukemia
- Apoptosis
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Colorectal cancer
- Endometrial cancer
- ErbB signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Glioma
- Inositol phosphate metabolism
- Insulin signaling pathway
- Jak-STAT signaling pathway
- Leukocyte transendothelial migration
- Melanoma
- mTOR signaling pathway
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- Pancreatic cancer
- Pathways in cancer
- Phosphatidylinositol signaling system
- Prostate cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Small cell lung cancer
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
- Type II diabetes mellitus
- VEGF signaling pathway
- Related Disease
- Adenocarcinoma
- Adenocarcinoma, Mucinous
- Adenocarcinoma, Papillary
- Adenoma
- Adenomatous Polyposis Coli
- Alzheimer Disease
- Alzheimer disease
- Astrocytoma
- Barrett Esophagus
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma in Situ
- Carcinoma, Ductal, Breast
- Carcinoma, Intraductal, Noninfiltrating
- Carcinoma, Lobular
- Carcinoma, Papillary
- Carcinoma, Papillary, Follicular