重组人泛素结合酶E2-K(UBCE2K)
产品名称: 重组人泛素结合酶E2-K(UBCE2K)
英文名称: Recombinant Human Ubiquitin-Conjugating Enzyme E2 K
产品编号: HZ1035
产品价格: 0
产品产地: 中国/上海
品牌商标: 沪震生物
更新时间: 2023-08-17T10:24:20
使用范围: null
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重组人泛素结合酶E2-K(UBCE2K)
中文名称:重组人泛素结合酶E2-K(UBCE2K)
英文名称:Recombinant Human Ubiquitin-Conjugating Enzyme E2 K
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Asn200在N端带有GST标签。
UBE2K质量控制:>95%(还原性SDS-PAGE)
UBE2K制剂:液体
UBE2K保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于UBE2K:
Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimers disease, Huntingtons disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.
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