FITC标记的膀胱癌相关蛋白BLCAP抗体
产品名称： FITC标记的膀胱癌相关蛋白BLCAP抗体
英文名称： Anti-BLCAP/FITC
产品编号： HZ-18477R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-BLCAP/FITC Conjugated antibody
FITC标记的膀胱癌相关蛋白BLCAP抗体
| 英文名称 | Anti-BLCAP/FITC |
| 中文名称 | FITC标记的膀胱癌相关蛋白BLCAP抗体 |
| 别 名 | Bc10; Bladder cancer 10 kDa protein; Bladder cancer related protein (10kD); Bladder cancer-associated protein; BLCAP; BLCAP_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 10kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BLCAP |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. This gene is imprinted in brain where it is differentially expressed from different promoters. Transcription from the upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2009] Function: May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B. Subcellular Location: Membrane. Tissue Specificity: Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas. Similarity: Belongs to the BLCAP family. Database links: Entrez Gene: 10904 Human Entrez Gene: 53619 Mouse Entrez Gene: 171113 Rat Omim: 613110 Human SwissProt: P62952 Human SwissProt: P62951 Mouse SwissProt: P62950 Rat Unigene: 472651 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一种肿瘤抑制蛋白，通过刺激细胞凋亡来减少细胞生长。该基因的第一内含子含有神经突触素基因，该基因被印迹并仅从父本等位基因表达。该基因在不同的启动子差异表达的脑中被印迹。上游启动子的转录优先发生在母体等位基因上，而转录子优先表达于父体等位基因上的下游启动子。替代启动子和替代剪接导致编码相同蛋白的多个转录体变体。