SENP8 MaxPab rabbit polyclonal antibody (D01)
产品名称： SENP8 MaxPab rabbit polyclonal antibody (D01)
英文名称： SENP8 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00123228-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human SENP8 protein.
- Immunogen:
- SENP8 (NP_660205.2, 1 a.a. ~ 212 a.a) full-length human protein.
- Sequence:
- MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLIATLAKK
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Publication Reference
- 1.
- Central Role for Endothelial Human Deneddylase-1/SENP8 in Fine-Tuning the Vascular Inflammatory Response.
Ehrentraut SF, Kominsky DJ, Glover LE, Campbell EL, Kelly CJ, Bowers BE, Bayless AJ, Colgan SP.J Immunol. 2012 Dec 3.
- Applications
- Western Blot (Tissue lysate)
- SENP8 MaxPab rabbit polyclonal antibody. Western Blot analysis of SENP8 expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of SENP8 expression in transfected 293T cell line (H00123228-T01) by SENP8 MaxPab polyclonal antibody.
Lane 1: SENP8 transfected lysate(24.1 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of SENP8 transfected lysate using anti-SENP8 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SENP8 monoclonal antibody (M06), clone 2E1 (H00123228-M06).
- Protocol Download
- Entrez GeneID:
- 123228
- GeneBank Accession#:
- NM_145204.2
- Protein Accession#:
- NP_660205.2
- Gene Name:
- SENP8
- Gene Alias:
- DEN1,HsT17512,NEDP1,PRSC2
- Gene Description:
- SUMO/sentrin specific peptidase family member 8
- Omim ID:
- 608659
- Gene Ontology:
- Hyperlink
- Gene Summary:
- NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM
- Other Designations:
- NEDD8-specific protease 1,SUMO/sentrin specific protease family member 8,deneddylase 1,protease, cysteine, 2 (NEDD8 specific),sentrin/SUMO-specific protease SENP8