FITC标记的EML2蛋白抗体
产品名称: FITC标记的EML2蛋白抗体
英文名称: Anti-EML2/FITC
产品编号: HZ-20006R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EML2/FITC Conjugated antibody
FITC标记的EML2蛋白抗体
英文名称Anti-EML2/FITC中文名称FITC标记的EML2蛋白抗体别 名1600029N02Rik; Echinoderm microtubule associated protein like 2; Echinoderm microtubule-associated protein-like 2; Echinoderm MT associated protein like protein 70; ELP70; EMAL2_HUMAN; EMAP-2; EMAP2; EML2; HuEMAP-2. 规格价格100ul/2980元 购买 大包装/询价说 明 书100ul 研究领域细胞生物 神经生物学 信号转导 细胞凋亡 细胞骨架 抗体来源Rabbit克隆类型Polyclonal交叉反应产品应用ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.分 子 量71kDa性 状Lyophilized or Liquid浓 度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human EML2亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.产品介绍background: Microtubules are components of the actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML2 (echinoderm microtubule associated protein like 2), also known as ELP70, EMAP2 or EMAPL2, is a cytoplasmic protein that acts to elongate microtubules, while at the same time making them more dynamic. Like other members of the EML family, EML2 contains a hydrophobic ELP (HELP) domain and a large WD repeat domain, both of which allow EML2 to participate in cytoskeleton assembly. Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Subcellular Location: Cytoplasm; cytoskeleton. Tissue Specificity: Ubiquitous. Similarity: Belongs to the WD repeat EMAP family. Contains 11 WD repeats. Database links: Entrez Gene: 24139 Human Entrez Gene: 72205 Mouse Entrez Gene: 192360 Rat SwissProt: O95834 Human SwissProt: Q7TNG5 Mouse SwissProt: Q6P6T4 Rat Unigene: 24178 Human Unigene: 154121 Mouse Unigene: 76362 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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微管是肌动蛋白细胞骨架的组成部分,在细胞形态发生、细胞运动、纺锤体形成和染色体运动中起着关键作用。棘皮动物微管相关(EML)蛋白的功能是改变微管的组装动力学。EML2(棘皮微管相关蛋白如2),也称为ELP70、EMAP2或EMAPL2,是一种细胞质蛋白,其作用是使微管伸长,同时使它们更有活力。像EML家族的其他成员一样,EML2包含疏水性ELP(HELP)结构域和大的WD重复结构域,这两个结构域都允许EML2参与