Anti-DPH3/FITC Conjugated抗体
产品名称： Anti-DPH3/FITC Conjugated抗体
英文名称： Anti-DPH3/FITC
产品编号： YB--14416R-FITC
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-DPH3/FITC Conjugated抗体
| 产品编号 | YB-14416R-FITC |
| 英文名称 | Anti-DPH3/FITC |
| 中文名称 | FITC标记的DPH3蛋白抗体 |
| 别 名 | CSL-type zinc finger-containing protein 2; Deafness locus putative guanine nucleotide exchange factor interacting protein 1; DelGEF-interacting protein 1; DELGIP; DelGIP1; DESR1; Diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1; DPH3; DPH3 homolog; DPH3 KTI11 homolog; DPH3_HUMAN; DPH3A; KTI11; MGC20197; ZCSL2; Zinc finger CSL domain containing 2; Zinc finger CSL type containing 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 细菌及病毒 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 9.2kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DPH3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009] Function: Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A. Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung. Similarity: Belongs to the DPH3 family. Contains 1 DPH-type zinc finger. Database links: Entrez Gene: 285381 Human Omim: 608959 Human SwissProt: Q96FX2 Human Unigene: 388087 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |