FITC标记的磷酸化蛋白酪氨酸激酶9抗体
产品名称： FITC标记的磷酸化蛋白酪氨酸激酶9抗体
英文名称： Anti-phospho-PTK9 (Tyr321)/FITC
产品编号： HZ-5613R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-phospho-PTK9 (Tyr321)/FITC Conjugated antibody
FITC标记的磷酸化蛋白酪氨酸激酶9抗体
| 英文名称 | Anti-phospho-PTK9 (Tyr321)/FITC |
| 中文名称 | FITC标记的磷酸化蛋白酪氨酸激酶9抗体 |
| 别 名 | PTK9 (phospho-Tyr321); PTK9 (phospho-Y321); p-PTK9 (Tyr321); p-TWF1(Y321); A6; A6 protein tyrosine kinase; Protein A6; Protein tyrosine kinase 9; PTK9; PTK9 protein tyrosine kinase 9; TWF 1; TWF1; Twinfilin 1; Twinfilin actin binding protein, homolog 1; Twinfilin; Twinfilin, actin-binding protein, homolog 1 (Drosophila); Twinfilin, Drosophila, homolog of, 1; TWF1_HUMAN; Twinfilin-1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 免疫学 信号转导 结合蛋白 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human TWF1 around the phosphorylation site of Tyr321 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. Subunit: Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF2 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down-regulated. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts. Tissue Specificity: Expressed at high levels in the colon, testis, ovary, prostate and lung. Expressed at lower levels in the brain, bladder and heart. Not detected in liver. Post-translational modifications: Phosphorylated on serine and threonine residues. Similarity: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. Contains 2 ADF-H domains. Database links: Entrez Gene: 5756 Human Entrez Gene: 506683 Cow Entrez Gene: 19230 Mouse Entrez Gene: 315265 Rat Omim: 610932 Human SwissProt: Q56JV6 Cow SwissProt: Q12792 Human SwissProt: Q91YR1 Mouse SwissProt: Q5RJR2 Rat Unigene: 5944 Cow Unigene: 189075 Human Unigene: 309867 Mouse Unigene: 162971 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
PTK9是一种参与运动和形态过程的肌动蛋白结合蛋白。它抑制肌动蛋白聚合，可能通过螯合G-肌动蛋白。通过覆盖丝的倒刺端，它也调节运动。PTK9似乎在网格蛋白介导的内吞作用和内吞细胞器的分布中起重要作用。