SYNGAP1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SYNGAP1 抗体

SYNGAP1 抗体

商家询价

产品名称： SYNGAP1 抗体

英文名称： SYNGAP1 Antibody

产品编号： XY19739-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 SYNGAP1 抗体Applications

Tested Applications: ELISA, WB, IF, IP
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Mouse brain tissue
Positive IP detected in Mouse brain tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:1000-1:10000
IP : 1:200-1:2000
IF : 1:10-1:100
 SYNGAP1 抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 19739-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 19739-1-AP(SYNGAP1 antibody) at dilution of 1:500
  • 19739-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using SYNGAP1 antibody 19739-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
  • 19739-1-AP;mouse brain tissueIP Result of anti-SYNGAP1 (IP:19739-1-AP, 4ug; Detection:19739-1-AP 1:500) with mouse brain tissue lysate 4000ug.
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information SYNGAP1 抗体
Immunogen: Peptide Full Name: Synaptic Ras GTPase activating protein 1 homolog (rat)
Caculated Molecular
Weight:		 1343aa,148 kDa Observed Molecular 
Weight:		 148 kDa
GenbankNo NM_006772 GeneID: 8831
Symbol SYNGAP1 Synonyms DKFZp761G1421, KIAA1938, MRD5, Neuronal RasGAP, RASA1, RASA5, Synaptic Ras GAP 1, SYNGAP, SYNGAP1
Background

SYNGAP1, also named as KIAA1938, is the major constituent of the PSD essential for postsynaptic signaling. It’s an inhibitory regulator of the Ras-cAMP pathway. SYNGAP1 is a member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. SYNGAP1 regulates AMPAR-mediated miniature excitatory postsynaptic currents. SYNGAP1 may be involved in certain forms of brain injury, leading to long-term learning and memory deficits Defects in SYNGAP1 are the cause of mental retardation autosomal dominant type 5 (MRD5). SYNGAP1 抗体

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