SEPT10,细胞分化蛋白SEPT10抗体

产品编号HZ-7770R
英文名称SEPT10
中文名称细胞分化蛋白SEPT10抗体
别 名SEPT 10; SEPT-10; Septin 10; Septin-10; Septin 10; SEP10_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 细胞周期蛋白 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit,
SEPT10,细胞分化蛋白SEPT10抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SEPT10
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SEPT10,细胞分化蛋白SEPT10抗体PubMedPubMed
产品介绍background:
The SEPT10 gene encodes a member of the septin family of cytoskeletal proteins which have GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms.

Function:
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).

Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein, detected in the nucleus (PubMed:12711328).

Tissue Specificity:
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.

SEPT10,细胞分化蛋白SEPT10抗体Similarity:
Belongs to the septin family.

Gene ID:
151011

Database links:
Entrez Gene: 151011 Human
Entrez Gene: 103080 Mouse
Omim: 611737 Human
SwissProt: Q9P0V9 Human
SwissProt: Q8C650 Mouse
Unigene: 469615 Human
Unigene: 346842 Mouse
Unigene: 397041 Mouse

SEPT10,细胞分化蛋白SEPT10抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SEPTIN(SEPT)家族是细胞骨架蛋白的一种，具有GTPase的活性。经研究发現，SEPT参与细胞核分裂、细胞膜的运输以及构成细胞骨架。