Anti-GM-CSF抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-GM-CSF抗体

Anti-GM-CSF抗体

商家询价

产品名称: Anti-GM-CSF抗体

英文名称: GM-CSF

产品编号: YB--3790R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-GM-CSF抗体

产品编号 YB-3790R
英文名称 GM-CSF
中文名称 粒细胞-巨噬细胞克隆刺激因子抗体
别    名 Granulocyte-Macrophage Colony Stimulating Factor; Burst Promoting Activity; CMCSF; Colony Stimulating Factor 2; Colony stimulating factor; CSF 2; CSF Alpha; CSF; CSF2; Eosinophil Colony Stimulating Factor; GMCSF; Granulocyte Macrophage Colony Stimulating Factor; MGC131935; MGC138897; Molgramostin; Pluripoietin Alpha; Sargramostim; granulocyte-macrophage colony-stimulating factor precursor; CSF2_HUMAN.   
Specific References  (1)     |     bs-3790R has been referenced in 1 publications.
[IF=0.30] Li, Zhen, et al. "Methods for transferring gene into silkworm and expression of hGM-CSF in silk glands of transgenic silkworm." Journal of Chemical and Pharmaceutical Research 6.5 (2014): 118-129.  WB ;  
PubMed:21533901
 
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  免疫学  信号转导  趋化因子  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GM-CSF:65-144/144 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq, Jul 2008].

Function:
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Subunit:
Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.

Subcellular Location:
Secreted.

Similarity:
Belongs to the GM-CSF family.

SWISS:
P04141

Gene ID:
1437

Database links:

Entrez Gene: 1437 Human

Omim: 138960 Human

SwissProt: P04141 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

GM-CSF是血管内皮细胞、单核细胞和成纤维细胞合成的糖蛋白。能促进中性粒细胞成熟;刺激成熟的粒细胞从骨髓释出;增强中性粒细胞趋化及吞噬功能